[HTML][HTML] Legacy of the influenza pandemic 1918: The host T cell response
AJ McMichael - biomedical journal, 2018 - Elsevier
AJ McMichael
biomedical journal, 2018•ElsevierThe influenza virus was instrumental in unravelling critical aspects of the antiviral T
lymphocyte mediated immune response. A major finding was the demonstration that CD8 T
lymphocytes recognize short viral peptides presented by class I molecules of the major
histocompatibility complex. Studies of influenza specific T cells have also led to an
understanding of their important role in recovery from influenza virus infection in humans.
lymphocyte mediated immune response. A major finding was the demonstration that CD8 T
lymphocytes recognize short viral peptides presented by class I molecules of the major
histocompatibility complex. Studies of influenza specific T cells have also led to an
understanding of their important role in recovery from influenza virus infection in humans.
Abstract
The influenza virus was instrumental in unravelling critical aspects of the antiviral T lymphocyte mediated immune response. A major finding was the demonstration that CD8 T lymphocytes recognize short viral peptides presented by class I molecules of the major histocompatibility complex. Studies of influenza specific T cells have also led to an understanding of their important role in recovery from influenza virus infection in humans.
Elsevier
